The St. Croix Radiosondes CPEX-AW dataset consists of atmospheric pressure, atmospheric temperature, relative humidity, wind speed, and wind direction measurements. These measurements were taken from the DFM-09 Radiosonde instrument during the Convective Processes Experiment – Aerosols & Winds (CPEX-AW) field campaign. CPEX-AW was a joint effort between the US National Aeronautics and Space Administration (NASA) and the European Space Agency (ESA) with the primary goal of conducting a post-launch calibration and validation activities of the Atmospheric Dynamics Mission-Aeolus (ADM-AEOLUS) Earth observation wind Lidar satellite in St. Croix, U.S. Virgin Islands. Data are available from August 19, 2021 through September 14, 2021 in netCDF and ASCII formats, with associated browse imagery in PNG format.