A study of gene expression influenced by simulated microgravity in human lymphoblastoid cells

Here in this study we systematically examined the patterns of DNA methylation and hydroxy-methylation with its functional implications in gene regulation for the cultured TK6 lymphoblastoid cells upon exposure to micro-gravity conditions. The results reported here indicate that simulated microgravity alters methylation patterns in a limited way and subsequently the expression of genes involved in stress response like ATF3 FBXO17 MAP3K13 and VCL in TK6 cells. Overall design: Examination of RNA-seq with 2 replicates each for 1 cell type

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Additional Info

Field Value
Maintainer GeneLab Outreach
Last Updated April 23, 2025, 20:02 (UTC)
Created February 19, 2025, 04:05 (UTC)
accessLevel public
accrualPeriodicity irregular
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harvest_source_title DNG Legacy Data
identifier nasa_genelab_GLDS-91_bjtj-w8rd
issued 2018-06-26
landingPage https://data.nasa.gov/dataset/a-study-of-gene-expression-influenced-by-simulated-microgravity-in-human-lymphoblastoid-ce
modified 2023-01-26
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publisher National Aeronautics and Space Administration
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