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Synergistic effects of space radiation and microgravity (miRNA WT and dys-mutant)
Space radiations and microgravity both could cause DNA damage in cells but the effects of microgravity on DNA damage response to space radiations are still controversial. A mRNA... -
Dynamic gene expression response to altered gravity in human myelomonocytic...
We investigated differentially regulated genes in human myelomonocytic U937 cells in 20s and 5min microgravity and in hypergravity and compared expression profiles to identify... -
Identification of miRNAs involved in cell response to ionising radiation and...
BACKGROUND: Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis initiation.... -
Global gene expression analysis highlights microgravity sensitive key genes...
Microgravity exposure as well as chronic muscle disuse are two of the main causes of physiological adaptive skeletal muscle atrophy in humans and murine animals in physiological... -
Gravitational signature of synchronized cell cultures in particular cell cycle stages
Cell cycle and cell proliferation are decoupled under altered gravity conditions. We have previously shown that semisolid cell cultures of Arabidopsis suffer overall genome... -
Spaceflight effects on the mouse retina: Histological gene expression and...
We report the findings of an animal experiment onboard STS-135 investigating the molecular aspects of the impact of spaceflight on retinal biology by performing differential... -
Global gene expression analysis highlights microgravity sensitive key genes...
Microgravity exposure as well as chronic muscle disuse are two of the main causes of physiological adaptive skeletal muscle atrophy in humans and murine animals in physiological... -
Synergistic effects of space radiation and microgravity (miRNA WT and ced-1 mutant)
Space radiations and microgravity both could cause DNA damage in cells but the effects of microgravity on DNA damage response to space radiations are still controversial. A mRNA... -
Gravitational signature of synchronized cell cultures in particular cell cycle stages
Cell cycle and cell proliferation are decoupled under altered gravity conditions. We have previously shown that semisolid cell cultures of Arabidopsis suffer overall genome... -
Global DNA methylation profiling of radiation-induced rat mammary carcinomas
To investigate DNA methylation patterns in rat mammary carcinomas induced by ionizing radiation. DNA methylation patterns were analyzed in radiation-induced rat mammary... -
Global gene expression analysis highlights microgravity sensitive key genes...
Microgravity as well as chronic muscle disuse are two causes of low back pain originated at least in part from paraspinal muscle deconditioning. At present no study investigated... -
Identification of miRNAs involved in cell response to ionising radiation and...
BACKGROUND: Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis initiation.... -
Gene expression profiling of PBL in response to ionising radiation and...
BACKGROUND: Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis initiation.... -
Effects of 21 days of bedrest on human skeletal muscle gene expression
The present study concerns the effects of 21 days of sustained recumbence (bedrest) on skeletal muscle gene expression. 14 male subjects participated in normoxic bedrest (NBR)... -
Effect of acute muscle unloading on soleus and gastrocnemius muscle gene expression
Gene expression changes induced by acute skeletal muscle unloading which leads to physiological changes including muscle atrophy fibre-type switching and loss of ability to... -
mRNA expression profile in DLD-1 and MOLT-4 cancer cell lines cultured under...
DLD-1 and MOLT-4 cell lines were cultured in a Rotating cell culture system to simulate microgravity and mRNA expression profile was observed in comparison to Static controls.... -
Dynamic gene expression response to altered gravity in human T cells...
We investigated differentially regulated genes in human Jurkat T lymphocytic cells in 20s and 5min microgravity and in hypergravity and compared expression profiles to identify... -
Global gene expression profiling of radiation-induced rat mammary carcinomas
To investigate gene expression patterns in rat mammary carcinomas induced by ionizing radiation. Gene expression patterns were analyzed in radiation-induced rat mammary... -
Gene expression response to simulated gravity and hypergravity in human T cells
We investigated differentially regulated and stably expressed genes in human Jurkat T lymphocytic cells in 5min simulated microgravity and hypergravity and compared expression... -
Gene expression response to simulated gravity and hypergravity in human T cells
We investigated differentially regulated and stably expressed genes in human Jurkat T lymphocytic cells in 5min simulated microgravity and hypergravity and compared expression...