-
A study of alterations DNA epigenetic modifiincations (5mC and 5hmC)...
Here in this study we systematically examined the patterns of DNA methylation and hydroxy-methylation with its functional implications in gene regulation for the cultured TK6... -
mRNA expression profile in DLD-1 and MOLT-4 cancer cell lines cultured under...
DLD-1 and MOLT-4 cell lines were cultured in a rotating cell culture system to simulate microgravity and mRNA expression profile in comparison to Static controls. Cells were... -
HARV replication of the BRIC-23 Bacillus subtilis spaceflight
Previous spaceflight experiments using Bacillus subtilis have reported altered transcriptome profiles during spaceflight compared to matching ground samples. This study tried to... -
T Cell Activation in Microgravity Compared to 1g (Earth s) Gravity
This study tested the hypothesis that transcription of immediate early genes is inhibited in T cells activated in microgravity (uG). Immunosuppression during spaceflight is a... -
Gravitational signature of synchronized cell cultures in particular cell cycle stages
Cell cycle and cell proliferation are decoupled under altered gravity conditions. We have previously shown that semisolid cell cultures of Arabidopsis suffer overall genome... -
HARV replication of the BRIC-21 Bacillus subtilis spaceflight samples
Previous spaceflight experiments using Bacillus subtilis have reported altered transcriptome profiles during spaceflight compared to matching ground samples. This study tried to... -
Response of Pseudomonas aeruginosa PAO1 to low shear modeled microgravity
Anticipating the risk for infectious disease during space exploration and habitation is a critical factor to ensure safety health and performance of the crewmembers. As a... -
Transcription profiling of mouse osteoblasts under static vs simulated microgravity
The total RNA was extracted from 2T3 pre-osteoblast cells exposed to static or simulated microgravity (Rotating Wall Vessel) conditions. The RNA was then sent to Affymetrix... -
Global gene expression profiles of cardiac progenitors differentiated from...
Efficient generation of cardiomyocytes from human pluripotent stem cells is critical for their regenerative applications. Microgravity and 3D culture can profoundly modulate... -
Effect of microgravity on HUVECs (Human Umbilical vein Endothelial cells)...
Adaptation of humans in low gravity conditions is a matter of utmost importance when efforts are on to a gigantic leap in human space expeditions for tourism and formation of... -
A study of gene expression influenced by simulated microgravity in human...
Here in this study we systematically examined the patterns of DNA methylation and hydroxy-methylation with its functional implications in gene regulation for the cultured TK6... -
Effect of simulated microgravity on E. coli K12 MG1655 growth and gene expression
This study demonstrates simulated microgravity effects on E. coli K 12 MG1655 when grown on LB medium supplemented with glycerol. The results imply that E. coli readily...