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Transcription profiling of atm mutant adm mutant and wild type whole plants...
Whole seedlings of wild type (4d) and atm mutants (4d) have been analyzed after a gamma ray irradiation of 0.75h 1.5h 3h & 5h (time course). Roots of wt (4d) atm (3d) and... -
A study of alterations DNA epigenetic modifiincations (5mC and 5hmC)...
Here in this study we systematically examined the patterns of DNA methylation and hydroxy-methylation with its functional implications in gene regulation for the cultured TK6... -
Expression data from rice calli cultured with 2,4-D
Four days old rice calli were selected to grow 324h under spaceflight controls 1g-flight controls and 1g-ground controls. We used microarrays to detail the global programme of... -
Exposure to ionizing radiation induced persistent gene expression changes in...
Six to eight week old female C57BL/6J mice were exposed to 2 Gy of whole body xce xb3 radiation and mammary glands were surgically removed 2-month after radiation. RNA was... -
Molecular mechanism of flocculation self-recognition in yeast and its role...
Saccharomyces cerevisiae flocculation occurs when fermentable sugars are limiting and is therefore considered as a way to enhance the survival chance of Flo-expressing yeast... -
Spaceflight effects on the mouse retina: Histological gene expression and...
We report the findings of an animal experiment onboard STS-135 investigating the molecular aspects of the impact of spaceflight on retinal biology by performing differential... -
MicroRNA expression of C. elegans in space environment
Entire microRNA expression were analyzed using the Filgen Array miRNA Caenorhabditis elegans 232 probes (Filgen). In the microRNA expression analysis we compared the expression... -
Biological Research in Canisters-16 (BRIC-16): Investigations of the plant...
These investigations studied the fundamentals of how plants perceive gravity and develop in microgravity. It informs how gene regulation is altered by spaceflight conditions. -
Microarray Analysis of Space-flown Murine Thymus Tissue
Microarray Analysis of Space-flown Murine Thymus Tissue Reveals Changes in Gene Expression Regulating Stress and Glucocorticoid Receptors. We used microarrays to detail the gene... -
Gene expression data from 4T1 irradiated tumors treated with TGFbeta blockade
Accumulating data support the concept that ionizing radiation therapy (RT) has the potential to convert the tumor into an in situ individualized vaccine; however this potential... -
Characterization of Epigenetic Regulation in an Extraterrestrial...
When germinated and grown on-board the ISS (International Space Station) plant do not exhibit abnormal structures but they do have altered growth habits and this project aims to... -
mRNA expression profile in DLD-1 and MOLT-4 cancer cell lines cultured under...
DLD-1 and MOLT-4 cell lines were cultured in a rotating cell culture system to simulate microgravity and mRNA expression profile in comparison to Static controls. Cells were... -
Chronic low dose-rate versus acute ionizing radiation induced gene...
Using a novel flood source construct we performed a direct comparison of genome-wide gene expression regulations resulting from exposure of primary human prostate fibroblast... -
A whole-genome microarray study of Arabidopsis thaliana cell cultures...
Arabidopsis thaliana wild type cell cultures were exposed to a 5-day space flight onboard of Shenzhou 8 to identify microgravity and space effect related gene expression. -
Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived...
With extended stays aboard the International Space Station (ISS) becoming commonplace there is a need to better understand the effects of microgravity on cardiac function. We... -
Exposure of zebrafish larvae to 3g and 5g hyper gravity between 5-6 days...
The general objective of the study was to determine modulation of gene expression by environmental factors, with a special emphasis on bone formation. For this reason, the... -
Transcription profiling of Arabidopsis seedings exposed to UV-B irradiation
Interaction of COP1 and UVR8 which regulate UV-B-induced photomorphogenesis and stress acclimation in Arabidopsis thaliana. -
Radiation-induced bystander effects and gene expression in cells deficient for RAD9
Background: The radiation bystander response is an important component of the overall response of cells to radiation and critical to understanding health risks of radiation... -
Exposure of zebrafish larvae to relative microgravity between 5-6 days...
The general objective of the study was to determine modulation of gene expression by environmental factors with a special emphasis on bone formation. For this reason the... -
Gravitational signature of synchronized cell cultures in particular cell cycle stages
Cell cycle and cell proliferation are decoupled under altered gravity conditions. We have previously shown that semisolid cell cultures of Arabidopsis suffer overall genome...