-
HARV replication of the BRIC-23 Bacillus subtilis spaceflight
Previous spaceflight experiments using Bacillus subtilis have reported altered transcriptome profiles during spaceflight compared to matching ground samples. This study tried to... -
Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived...
With extended stays aboard the International Space Station (ISS) becoming commonplace there is a need to better understand the effects of microgravity on cardiac function. We... -
miRNA signature detection and countermeasures against HZE radiation exposure...
Biological risks associated with space radiation and microgravity are major concerns for long-term space travel. Through a Systems Biology approach our previous NASA work has... -
Plasticity of the human IgM repertoire in response to a long-term spaceflight
Immune dysregulation is among the main adverse outcomes of spaceflight. Despite its crucial role in host protection effects on the human antibody repertoire are unknown.... -
Whole Metagenome Profiles of Particulates Collected from the International...
The microbial composition of the International Space Station (ISS) environment is of critical interest due to potential impact of its constituents on human health and... -
Transcriptomic analysis of quadriceps from mice subjected to simulated...
To understand the molecular mechanisms affected by spaceflight it is essential to achieve high quality sample preservation on-orbit for downstream gene expression analysis.... -
Rodent Research-3-CASIS: Mouse kidney transcriptomic proteomic and epigenomic data
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Impact of Antiorthostatic Suspension on Mouse response to Tetanus Toxoid and CpG
These data were generated from mice that were skeletally unloaded using antiorthostatic suspension (AOS). Mice were either subjected to AOS or tail restraint without unloading... -
Genes Required for Survival in Microgravity Revealed by Genome-Wide Yeast...
Spaceflight is a unique environment with profound effects on biological systems including tissue redistribution and musculoskeletal stresses. However the more subtle biological... -
Rodent Research-1 (RR1) NASA Validation Flight: Mouse quadriceps muscle...
NASA s Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited resources... -
Rodent Research-3-CASIS: Mouse liver transcriptomic proteomic and epigenomic data
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Muscle atrophy osteoporosis prevention in hibernating mammals
Physical inactivity decreases the mechanical load on the skeleton which when prolonged leads to losses of muscle strength and bone mass in humans and most mammalian species.... -
Temporal dynamics of the gut microbiota in people sharing a confined...
The MARS500 project the longest ground-based space simulation ever provided us with a unique opportunity to trace the crew microbiota over 520 days of isolated confinement such... -
Microbial monitoring in the ISS-Kibo
Continuous monitoring of bacterial community structure in the ISS-Kibo. This data contains numerous sequence reads of 16S rRNA gene fragments. -
HARV replication of the BRIC-21 Bacillus subtilis spaceflight samples
Previous spaceflight experiments using Bacillus subtilis have reported altered transcriptome profiles during spaceflight compared to matching ground samples. This study tried to... -
RNAseq analysis of the response of Arabidopsis thaliana to fractional...
Traveling to nearby extraterrestrial objects having a reduced gravity level (partial gravity) compared to Earth's gravity is becoming a realistic objective for space agencies.... -
Comparative Transcriptomic Analysis of Adult Medaka Tissues Sampled after...
To understand how humans adapt to space environments many experiments can be conducted on astronauts while they work aboard the Space Shuttle or the International Space Station... -
Medaka Osteoclast
During space flight bone mineral density is decreased by the influence of osteoclast activation which molecular mechanism is expectantly investigated. In the study of medaka... -
Selecting for Chlamydomonas reinhardtii fitness in the KSC Veggie Unit
The Space Algae Experiment Verification Test completed a competitive growth selection on mutagenized microalgae in a series of batch cultures that were passaged for three growth... -
Transcriptomic analysis of femoral skin from mice flown on the MHU-2 mission
The JAXA MHU-2 mission had two objectives: 1) To increase understanding of effects of spaceflight on the gut environment (microbiota and metabolites) and immune system using...