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Transcription profiling of atm mutant adm mutant and wild type whole plants...
Whole seedlings of wild type (4d) and atm mutants (4d) have been analyzed after a gamma ray irradiation of 0.75h 1.5h 3h & 5h (time course). Roots of wt (4d) atm (3d) and... -
A study of alterations DNA epigenetic modifiincations (5mC and 5hmC)...
Here in this study we systematically examined the patterns of DNA methylation and hydroxy-methylation with its functional implications in gene regulation for the cultured TK6... -
Expression data from rice calli cultured with 2,4-D
Four days old rice calli were selected to grow 324h under spaceflight controls 1g-flight controls and 1g-ground controls. We used microarrays to detail the global programme of... -
Transcriptomic analysis of spleens from mice subjected to chronic low-dose...
The purpose of this study was to evaluate transcriptional changes in mouse spleens using a ground-based model for spaceflight. This model includes prolonged unloading and low-... -
miRNA signature detection and countermeasures against HZE radiation exposure...
Biological risks associated with space radiation and microgravity are major concerns for long-term space travel. Through a Systems Biology approach our previous NASA work has... -
Eruca sativa Rocket Science RNA-seq
In the Rocket Science citizen science project Eruca sativa (salad rocket) seeds stored for six months on board of the International Space Station caused delayed crop... -
Low dose (0.04 Gy) irradiation (LDR) and hindlimb unloading (HLU)...
The purpose of the present study was to evaluate damage in brain and eye in a ground-based model for spaceflight which includes prolonged unloading and low-dose radiation. Low-... -
Effects of 21 days of bedrest on human skeletal muscle gene expression
The present study concerns the effects of 21 days of sustained recumbence (bedrest) on skeletal muscle gene expression. 14 male subjects participated in normoxic bedrest (NBR)... -
miRNA signature detection and countermeasures against HZE radiation exposure...
Biological risks associated with space radiation and microgravity are major concerns for long-term space travel. Through a Systems Biology approach our previous NASA work has... -
Microarray Analysis of Space-flown Murine Thymus Tissue
Microarray Analysis of Space-flown Murine Thymus Tissue Reveals Changes in Gene Expression Regulating Stress and Glucocorticoid Receptors. We used microarrays to detail the gene... -
Response of the EPI-200 human 3-D skin model to high and low doses of protons
Accumulating data suggest that the biological responses to high and low doses of radiation are qualitatively different necessitating the direct study of low dose responses. Most... -
Characterization of Epigenetic Regulation in an Extraterrestrial...
When germinated and grown on-board the ISS (International Space Station) plant do not exhibit abnormal structures but they do have altered growth habits and this project aims to... -
Hindlimb suspension and reloading study
Analysis of effect of hindlimb suspension and reloading on C57Bl/6 mouse soleus muscle. Experimental groups examined: -Control mice 14 days -Hindlimb suspension for 7 days... -
A whole-genome microarray study of Arabidopsis thaliana cell cultures...
Arabidopsis thaliana wild type cell cultures were exposed to a 5-day space flight onboard of Shenzhou 8 to identify microgravity and space effect related gene expression. -
HARV replication of the BRIC-23 Bacillus subtilis spaceflight
Previous spaceflight experiments using Bacillus subtilis have reported altered transcriptome profiles during spaceflight compared to matching ground samples. This study tried to... -
Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived...
With extended stays aboard the International Space Station (ISS) becoming commonplace there is a need to better understand the effects of microgravity on cardiac function. We... -
miRNA signature detection and countermeasures against HZE radiation exposure...
Biological risks associated with space radiation and microgravity are major concerns for long-term space travel. Through a Systems Biology approach our previous NASA work has... -
Plasticity of the human IgM repertoire in response to a long-term spaceflight
Immune dysregulation is among the main adverse outcomes of spaceflight. Despite its crucial role in host protection effects on the human antibody repertoire are unknown.... -
Exposure of zebrafish larvae to 3g and 5g hyper gravity between 5-6 days...
The general objective of the study was to determine modulation of gene expression by environmental factors, with a special emphasis on bone formation. For this reason, the... -
Characterization of Epigenetic Regulation in an Extraterrestrial...
When germinated and grown on-board the ISS (International Space Station) plant do not exhibit abnormal structures but they do have altered growth habits and this project aims to...