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Transcriptional profiling of roots and shoots from Brachypodium distachyon...
Most major cereal grain crops are monocots. Yet, most investigations of plant adaptation to the spaceflight environment have been carried out on the dicotyledonous model plant,... -
Transcriptional profiling of cerebellums from mice flown on the RR-23 mission
The objective of the Rodent Research-23 missions (RR-23) was to better understand the effects of spaceflight on the eyes, specifically on the structure and function of the... -
Quantifying Cancellous Bone Structural Changes in Microgravity: Axial...
Objective of this study was to further validate bone degradation in microgravity as site-specific and preferential to weight bearing bone. An objective of this study was to... -
Rodent Research-3-CASIS: Mouse adrenal gland transcriptomic, proteomic, and...
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
STS-135: Mouse Liver Transcriptomics using RNA-Seq
Female C57BL/6CR mice were flown onboard STS-135 for 13 days and returned to Earth for analysis. Livers were collected within 3-4 hours of landing and snap frozen in liquid... -
Spaceflight-induced (STS-62) vertebral bone loss in ovariectomized rats is...
There is often a reciprocal relationship between bone marrow adipocytes and osteoblasts, suggesting that marrow adipose tissue (MAT) antagonizes osteoblast differentiation. MAT... -
Rodent Research-3-CASIS: Mouse eye transcriptomic and proteomic data
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Altered rodent gait characteristics after ~35 days in orbit aboard the...
The long-term adaptations to microgravity and other spaceflight challenges within the confines of a spacecraft, and readaptations to weight-bearing upon reaching a destination,... -
Fifteen days of microgravity causes growth in calvaria of mice (STS-131)
Bone growth may occur in spaceflight as a response to skeletal unloading and head-ward fluid shifts. While unloading causes significant loss of bone mass and density in legs of... -
Artificial gravity partially protects space-induced neurological deficits in...
Spaceflight poses risks to the central nervous system (CNS), and understanding neurological responses is important for future missions. We report CNS changes in Drosophila... -
Artificial gravity partially protects space-induced neurological deficits in...
Spaceflight poses risks to the central nervous system (CNS), and understanding neurological responses is important for future missions. We report CNS changes in Drosophila... -
Rodent Research-1 (RR1) NASA Validation Flight: Mouse eye transcriptomic and...
NASA's Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited resources... -
Artificial gravity partially protects space-induced neurological deficits in...
Spaceflight poses risks to the central nervous system (CNS), and understanding neurological responses is important for future missions. We report CNS changes in Drosophila... -
Transcriptional profiling of thymus tissue from rats flown on the SLS-2 mission
The Spacelab Life Sciences (SLS) program was a series of payloads that used the facilities of an entire Spacelab module to conduct a variety of life science investigations. The... -
Advancing the automation of plant nucleic acid extraction for rapid...
Human space exploration missions will continue the development of sustainable plant cultivation in what are obviously novel habitat settings. Effective pathology mitigation... -
Characterization of Biofilm Formation, Growth, and Gene Expression on...
Microorganisms' natural ability to live as organized multicellular communities – also known as biofilms – provides them with unique survival advantages. For instance, biofilms... -
Toward countering muscle and bone loss with spaceflight: GSK3 as a potential...
We examined the effects of ~30 days of spaceflight on glycogen synthase kinase 3 (GSK3) content and inhibitory serine phosphorylation in murine muscle and bone samples from four... -
Arg1 functions in the physiological adaptation of undifferentiated plant...
In this study transcriptome profiling was used to gain insight into the spaceflight adaptation role of Altered response to gravity-1 (Arg1), a gene known to affect gravity... -
HSFA2 functions in the physiological adaptation of undifferentiated plant...
The Heat Shock Factor A2 (HsfA2), as a part of the HSF network, is essential to the plant's response to almost any environmental stress and to the cellular homeostatic control... -
Comparing RNA-Seq and microarray gene expression data in two zones of the...
Premise of the study: The root apex is an important region involved in environmental sensing, but comprises a very small part of the root. Obtaining root apex transcriptomes is...